Veterynarna biotehnologija – Veterinary biotechnology, 2016, 28, 259-265 [in Ukrainian].
Poltava State Agrarian Academy
National University of Life and Environmental Sciences of Ukraine
Institute of Veterinary Medicine of NAAS
MACROSCOPIC CHANGES AT FELINE INFECTIOUS PERITONITIS
Introduction. Feline infectious peritonitis (FIP) is a subacute or chronic viral disease of wild and domestic cats caused by one of coronaviruses. The name of this disease is conditional, since among the variety of clinical symptoms, the most common is peritonitis. FIP is not inflammatory disease of the abdomen but rather vasculitis (inflammation of blood vessels). Infectious peritonitis was first described in 1966 by Wolfe and Griesemer. In our country, this disease is often registered in domestic cats. Among animals in zoos it is registered in manuls.
The goal of the work was studying of macroscopic changes in the organs and tissues of animals that died because of the FIP, establishing the relationship of morphological mechanism of death with morphological state of the organism.
Materials and methods. The material of the study was the bodies of six cats died from FIP.
Results of research and discussion. During the post-mortem examination of three of the six cats corpses we registered combination of features of exudative and dry form of the disease. The mucous membranes of the oral cavity are anemic, with the expressed icterus. Lungs are with expressed signs of lobar pneumonia – a dough consistency, from the surface of all the lobes have uneven dark brown, red and gray colors according the stages of the red and gray hepatization of the pathological process. The heart has conical shape. The ratio of the right and left ventricles are 1:4 under thickening of the wall of the right ventricle, narrowing of its cavity. This is a sign of compensatory of concentric hypertrophy of the right ventricle. Liver surface is torosed, subcapsular hematoma is registered on the surface, as well as the gray color foci denser than the parenchyma of organ – chronic fibrinous serohepatitis. There is a small amount of a thick bright yellow liquid in the abdomen. Studying stomach and intestines it was found chronic catarrhal gastroenteritis. There are diffuse diphtheric layers of bright yellow fibrin on the surface of the peritoneum, kidney capsule, and omentum.
Conclusions and prospects for further research. The key component of pathogenesis is mass lesion of walls of parenchymal organs’ blood vessels, mucous and serous membranes with viral pathogen resulting in violation of their porosity. Macroscopic pathological changes manifest as chronic fibrinous serohepatitis, haemorrhages on serous membranes, lobar pneumonia, serous splenitis, serous lymphadenitis, nephritis. The specific characters are diphtheric fibrin lays of small and large intestines, pleura, peritoneum, renal fascia, omentum, and seroplastic exudate in the abdomen.
Keywords: infectious peritonitis, cats, autopsy, macroscopic changes internal organs.