Bulletin "Veterinary biotechnology"

Veterynarna biotehnologija – Veterinary biotechnology, 2018, 32(1), 22-33 [in Ukrainian]. https://doi.org/10.31073/vet_biotech32(1)-1

GOLOVKO A.N., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., NAPNENKO O.О.e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., YUSHCHENKO A.Y.,

State Scientific Control Institute of Biotechnology and Strains of Microorganisms (SSCIBSM)

PRISKOKA V.А.

State Scientific and Research Institute of Laboratory Diagnostics and Veterinary and Sanitary Expertise

THE ROLE OF THE STATE SCIENTIFIC-CONTROL INSTITUTE OF BIOTECHNOLOGY AND STRAINS OF MICROORGANISMS ON SECUREMENT OF EPIDEMIC WELFARE OF UKRAINE

Introduction. In accordance with the Law of Ukraine "On Veterinary Medicine" state control and supervision over the safety and quality of veterinary drugs, immunobiological in particular, their testing for registration purposes is entrusted on the State Scientific-Control Institute of Biotechnology of strains of microorganisms (SSCIBSM).

The purpose of our work was to study the history of the establishment and development of the SSCIBSM.

Materials and methods. We used official texts and published documents. An information that we obtained was systemized and received a chronicle of the establishment and development of the Institute.

Results of research and discussion. The origins of the SSCIBSM range from the establishment of the People's Commissariat for Agriculture (Narkomzem) of the All-Russian State Center for Control of Veterinary Drugs and Feed. In 1976 in structure of ASCCVD were established eight regional scientific-control laboratories, among which there were two in Ukraine – West-Ukrainian in Lviv and Ukrainian in Kiev. Later, the Ukrainian branch of ASCCVD Veterinary drugs was reorganized into the State Scientific-Research Control Institute of Veterinary Medicinal Products and Feed Additives, and the Ukrainian Zonal Scientific-Control Laboratory which located in Kyiv, become a branch of this institute. On the way to creating the conditions for the proper performance of the assigned functions concerning the deposition and maintenance of strains of microorganisms, provision of their biological enterprises was created by the National center of strains of microorganisms. On the way to establishing a proper condition for implementation of the appointed functions of deposition and maintenance of strains of microorganisms to provision of biofactory, the National Center of Strains of Microorganisms was created. In 1998, Kyiv branch was reorganized into State Scientific-Control Institute of Biotechnology and Strains of Microorganisms. In the end of 2000, Doctor of Veterinary Science Golovko Anatolii was appointed to director of SSCIBSM. With his advent, a new wave of the institute's development began. In the initiative of the Director, a Laboratory of molecular biology and immunochemistry was created, which was subsequently reorganized into the Department of Molecular Biology. Department was equipped by devices for PCR and ELISA. A lot of efforts were made to accept a number of normative documents related to the production of veterinary medicinal products. These documents were developed in accordance with the World Organisation of Animal Health, European Union directives, European Pharmacopoeia and international standards. From 2006 to 2012, the Institute successfully carried out its activities under the direction of the Doctor of Veterinary Sciences Ushkalov Valeriy, which continued an activity started by Golovko Anatolii. Under the guidance of Ushkalov V. and with the assistance of Golovko A., the Vice-President of the National Academy of Agrarian Sciences of Ukraine, by an order of the Ministry of Education and Science was opened a Postgraduate education on the specialty 16.00.03 – Veterinary Microbiology, Epizootology, Infectious Diseases and Immunology. In 2012, the Institute was re-headed by Academician of the NAAS of Ukraine Golovko A., who founded new subdivision – the Center for Scientific Support to the Processes of Standartization, Metrology and Conformity Assessment and the Department of Scientific Support for Biosafety and Biorisks. Over the past 5 years, the Department of the Institute have been accredited for DSTU ISO 9001, DSTU ISO 17025 and DSTU ISO 17024.

Conclusions and prospects for further research. In February 2018, the SSCIBSM celebrated its 20th anniversary. In the course of 20 years of independent existence, a low-budget institution has developed into an authoritative scientific organization with international recognition. The perspective directions of the further activities are introduction of certification and accreditation system in the field of veterinary biological medicine production.

REFERENCES

  1. Horzheyev, V.M. (2014). Problemy zabezpechennya veterynarnoho blahopoluchchya tvarynnytstva [Problems of providing veterinary welfare of livestock] Naukovyy visnyk veterynarnoyi medytsyny − Scientific herald of veterinary medicine, 13(108), 5–9 [in Ukrainian].
  2. Napnenko, O.O. (2016). Istoriya stanovlennya systemy kontrolyu yakosti veterynarnykh imunobiolohichnykh zasobiv v Ukrayini [Reform of history quality control of veterinary immunobiological products]. Veterinarna bіotehnologіa – Veterinary biotechnology, 29, 184–195 [in Ukrainian].
  3. Zakon Ukrayiny "Pro veterynarnu medytsynu" [Law of Ukraine "On Veterinary Medicine"] (n.d.) zakon3.rada.gov.ua Retrieved from http://zakon3.rada.gov.ua/laws/show/2498–12 [in Ukrainian].
  4. Royina, O.M. (2007). Veterynariya v Ukrayini: normatyvni dokumenty [Veterinary in Ukraine: regulations]. Kyiv: KNH [in Ukrainian].
  5. Panyn, A.N. (2011). Vserossiyskiy Gosudarstvennyy Tsentr Kachestva I Standartizatsii Lekarstvennykh Sredstv Dlya Zhivotnykh I Kormov – 80 let [Federal State Budgetary Institution «The Russian State Center for Animal Feed and Drug Standardization and Quality» is 80] Veterinaria – Veterinary Medicine, 1, 5–11 [in Russian].
  6. Kotsyumbas, I.Ya. (2013). Slavnyy 40-richnyy yuviley DNDKI veterynarnykh preparativ ta kormovykh dobavok [Glorious 40th anniversary SSRCI veterinary drugs and feed additives]. Naukovo-tekhnichnyy byuleten Derzhavnoho naukovo-doslidnoho kontrolnoho instytutu veterynarnykh preparativ ta kormovykh dobavok i Instytutu biolohiyi tvaryn. Scientific and technical bulletin of the State Research Institute for Veterinary Medicine and Food Additives and Institute of Animal Biology, 16(2), 13–18. [in Ukrainian].
  7. Ivashchenko, N.V. (2008) Derzhavnyy naukovo-kontrol'nyy instytut biotekhnolohiyi i shtamiv mikroorhanizmiv – istoriya i suchasnist' [State Scientific Control Institute of Biotechnology and strains – Past and Present]. Veterinarna bіotehnologіja – Veterinary biotechnology, 13(1), 8–17 [in Ukrainian].
  8. Ushkalov, V.A., Postoenko, V.A., Chumachenko, V.V., Babkyn, M.V., Blotskaya, O.F., Parkhomenko, N.A. et al. (2008). Gosudarstvennyj nauchno-kontrol'nyj institut biotehnologii i shtammov mikroorganizmov – 10 let na sluzhbe veterinarnoj mediciny Ukrainy [The State Scientific and Control Institute of Biotechnology and strains of microorganisms – 10 years in the service of veterinary medicine of Ukraine]. Biotechnology in Kazakhstan: Problems and Perspectives of Innovative Development: Mezhdunarod. nauch.-prakt. konf., posvyashch. 50-letyyu NYY problem byolohycheskoy bezopasnosty NTsB MON RK (h. Almatы, Respublyka Kazakhstan, 19–21 maya 2008 h.) − International. scientific-practical. conf., dedicated. The 50th anniversary of the Scientific Research Institute for Biological Safety Problems of the National Security Ministry of the Republic of Kazakhstan (Almaty, Republic of Kazakhstan, May 19–21, 2008). (pp. 290–291). Almaty [in Russian].
  9. Akymenko, L.I. & Boyko, P.K. (2007). Pidtrymannya biotekhnolohichnykh kharakterystyk deponovanykh shtamiv – vazhlyva skladova yakosti imunobiolohichnykh preparativ [Maintenance of biotechnological characteristics of deposited strains is an important component of the quality of immunobiological drugs]. Naukovo-tekhnichnyy byuleten Derzhavnoho naukovo-doslidnoho kontrolnoho instytutu veterynarnykh preparativ ta kormovykh dobavok i Instytutu biolohiyi tvaryn. Scientific and technical bulletin of the State Research Institute for Veterinary Medicine and Food Additives and Institute of Animal Biology, 8, 3, 4, 221–226 [in Ukrainian].
  10. Ushkalov, V.A., Golovko, A.N., Akymenko, L.I., Babkyn, M.V. (2008). Znachenie i perspektivy razvitia Nacionalnogo centra shtammov mikroorganizmov GNKIBShM [Importance and prospects of the development of the National Center for Microorganism Strains SSCIBSM]. International. scientific-practical. conf., dedicated. The 50th anniversary of the Scientific Research Institute for Biological Safety Problems of the National Security Ministry of the Republic of Kazakhstan (Almaty, Republic of Kazakhstan, May 19–21, 2008). (pp. 291–292). Almaty [in Russian].
  11. Golovko, A.M. & Verbyckyj, P.I. (2003). Nalezhna vyrobnycha praktyka (GMP) ta nalezhna dystryb'jutors'ka praktyka (GDP) veterynarnykh preparative [Manufacturing practice (GMP) and distribution practice (GDP) veterinary drug]. Kyiv: Referat [in Ukrainian].
  12. Golovko, A.N., Ushkalov, V.A. & Napnenko, A.A. (2012). Byobezopasnost pry proyzvodstve veterynarnykh ymmunobyolohycheskykh preparatov [Biosafety in the production of veterinary immunobiological preparations]. Regional biosafety and biosecurity: moving towards international standards. 4-ya ezhehodnaya konferentsyya Assotsyatsyy byolohycheskoy bezopasnosty Tsentral'noy Azyy y Kavkaza − The 4th Annual Conference of the Association for Biosafety of Central Asia and the Caucasus. (pp 53–54). Almaty [in Russian].
  13. Golovko, A.M., Herman, V.V., Blotska, O.F., Napnenko, O.O. & Borsuk, A.M. (2006). Shlyakhy vyrishennya problemy kontrolyu kontaminatsiyi veterynarnykh imunobiolohichnykh preparativ storonnimy virusamy [Ways of solving the problem of controlling the contamination of veterinary immunobiological drugs by foreign viruses]. Veterynarna medytsyna: Mizhvidom. temat. nauk. zb. − Veterinary Medicine: intervet. thematic sciences collection, 86, 96–98 [in Ukrainian].
  14. Napnenko, O.O. (2013). Standartyzatsiya vaktsyn proty miksomatozu kroliv ta metodiv kontrolyuvannya yikh yakosti [Standardization of vaccines against myxomatosis and methods for controlling their quality] Veterinarna bіotehnologіa – Veterinary biotechnology, 23, 320–326 [in Ukrainian].
  15. Golovko, A.M., Babkin, M.V. & Napnenko, O.O. (2009). Standartyzatsiya zhyvykh vaktsyn proty klasychnoyi chumy svyney ta metodiv kontrolyuvannya yikh yakosti [Standardization of live vaccines against classical swine fever and methods for controlling their quality]. Naukovo-tekhnichnyy byuleten Derzhavnoho naukovo-doslidnoho kontrolnoho instytutu veterynarnykh preparativ ta kormovykh dobavok i Instytutu biolohiyi tvaryn. – Scientific and technical bulletin of the State Research Institute for Veterinary Medicine and Food Additives and Institute of Animal Biology, 10(3), 141–145 [in Ukrainian].

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