Bulletin "Veterinary biotechnology"

Veterynarna biotehnologija – Veterinary biotechnology, 2018, 32(1), 130-133 [in Russian]. https://doi.org/10.31073/vet_biotech32(1)-16

KRASOCHKO P.A.*e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., SNITKO T.V.**, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

* Vitebsk State Academy of Veterinary Medicine, Republic of Belarus

** Grodno State Agrarian University, Republic of Belarus


Introduction. Aspartic amino acid is a strong immunomodulator. Since immunomodulators do not directly affect microbes, they can avoid the problem of rapid occurrence of resistance. Aspartic acid is one of the amino acids that is synthesized in the body that makes up the protein. In the pituitary gland, aspartic amino acid stimulates the secretion of the following hormones: growth hormone, which stimulates the growth and recovery of cells. In addition, prolactin, a hormone that is known to stimulate the mammary glands and milk production, among other functions – luteinizing hormone, which participates in the reproductive system. In males, it plays a role in the synthesis of testosterone. In females, plays a role in ovulation.

The goal of the work: to determine the minimum concentration of asparagine amino acid suspension inhibiting the growth of a culture of bacteria isolated from cows of patients with postpartum endometritis.

Materials and methods. In terms of animal industry, the use of highly productive animals with low resistance topical application of immunotherapy in the system of preventive and therapeutic measures in diseases both communicable and non-communicable etiologies. We have conducted a number of studies to determine the minimum concentration of a suspension of aspartic amino acids that inhibit the growth of bacteria isolated from cows patients with postpartum endometritis.

Results of research and discussion. We found that the lowest concentration of the suspension of the aspartic amino acid, causing a bactericidal effect with respect to: E. coli, was 3%, Staph. epidermidis 2.5%, Staph. aureus-4%, Proteus vulgaris-3.9%, Staph. puogenes – 3,4%.

Conclusions and prospects for further research. It is assumed that when using aspartic acid for the treatment of endometritis bacterial etiology will enhance the antimicrobial activity of the medicinal preparations of this amino acid.

Keywords: aspartic amino acid, minimal inhibitory concentration.


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