Bulletin "Veterinary biotechnology"

Veterynarna biotehnologija – Veterinary biotechnology, 2018, 32(1), 134-138 [in Russian]. https://doi.org/10.31073/vet_biotech32(1)-17

KRASOCHKO P.A.*, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., SNITKO T.V.**e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Vitebsk State Academy of Veterinary Medicine, Republic of Belarus

** Grodno State Agrarian University, Republic of Belarus

ANTAGONISTIC ACTIVITY OF MICROFLORA TO THE LACTIMET AND BATINIOL PROBIOTICS DURING ENDOMETRITIS IN COWS

Introduction. Studies related to the use of a probiotic as a complete alternative to an antibiotic are underway. The use of probiotics to improve the condition of humans and animals is a well-established fact. Recently, many studies have stated that probiotic drugs improve health and the immune system, and also have anti-carcinogenic, antidiarrheal and hypocholesterolemic effects, improve the use of lactose. As is known, in the mechanism of action of probiotic microorganisms, suppression of growth of pathogenic and conditionally pathogenic microflora is of great importance. The antagonistic properties of bacilli are strainspecific, so far from all bacteria have antimicrobial activity. The antagonism of lactic acid bacteria is due to the production of lactic acid, which itself has a certain bactericidal action and causes a decrease in the pH of the medium to values unfavorable for many species of microorganisms.

The goal of the work: determine antagonistic activity against microorganisms isolated from cows of patients with postnatal endometritis.

Materials and methods. We carried out studies to determine the antagonistic activity of bacteria released in postpartum endometritis of cows with respect to the probiotic drug based on lactic acid and bifidobacteria "Lactimet" and the bacillus probiotic preparation "Bacynil". The results show that the main part of the stem to expand from the sick Posner endometritis Kors have high sensitivity to the probiotic preparation "Bacynil" and " Lactimet ".

Results of research and discussion. Most of the strains isolated from patients with postnatal cows endometritis are highly sensitive to the probiotic "Bacinil" and "Lactimet".

Conclusions and prospects for further research. The results of the study of antagonistic activity of probiotic preparations "Bacynil" and "Lactimet" against microorganisms isolated from patients with postnatal cervical endometritis indicate that these drugs can be used for preventive and therapeutic purposes to control postpartum endometritis.

Keywords: antagonistic activity, probiotics "Bacynil", "Lactimet"

REFERENCES

  1. Bezborodov, N.Ya. & Yakovleva, E.G. (1994). Lecheniye korov. bolnykh endometritami [Treatment of cows. patients with endometritis]. Zootekhniya – Zootechny, 2, 22–23 [in Russian].
  2. Panferova, O.V. (2003). Novyye metody povysheniya effektivnosti profilaktiki i lecheniya zabolevaniy reproduktivnykh organov korov [New methods to improve the effectiveness of prevention and treatment of diseases of the reproductive organs of cows]. Veterinarnaya patologiya – Veterinary pathology, 4, 50–52 [in Russian].
  3. Konyves, L., Szenci, O., Jurkovich, V., Tegzes, L., Tirin, A. et al. (2009). Risk assessment of postpartum uterine disease and consequences of puerperal metritis for subsequent metabolic status. reproduction and milk yield in dairy cows. Acta Vet Hung, 57, 155–169.
  4. Gilbert R.O. (1992). Bovine endometritis: the burden of proof. Cornell Vet, 82, 11–14.
  5. Salminen, S. & von Wright. A. (1998). Lactic Acid Bacteria in Health and Disease. in Lactic Acid Bacteria. Microbiology and Functional Aspects. Marcel: Dekker Inc. Newark.
  6. Ametani, H.T. (2000). Improved growth and viability of lactobacilli in the presence of Bacillus subtilis (natto). catalase. or subtilisin, Can. J. Microbiol., 46, 892–897.
  7. Jadamus, A. & Vahjen, W. (2001). Growth behaviour of a spore-forming probiotic strain in the gastrointestinal tract of broiler chicken and piglets. Arch. Tierernahr., 54, 1–17.
  8. Krasochko, P.A., Lomako, Yu.V., Zuykevich, T.A., Snitko, T.V., Golovneva, N.A., Shchetko, V. A. et al. (2015). Instruktsiya po primeneniyu preparata Laktimet [Instructions for use of the drug Lactimet]. Minsk: Institute of Microbiology of the National Academy of Sciences of Belarus [in Russian].
  9. Krasochko, P.A., Lomako, Yu.V., Mikhalyuk, A.N., Malets, A.V., Sanzharovskaya, Yu.M., Snitko, T.V. et al. (2016). Instruktsiya po primeneniyu preparata Batsinil [Instructions for use of the drug Batsinil]. Minsk: Institute of Microbiology of the National Academy of Sciences of Belarus [in Russian].

Download full text in PDF