Bulletin "Veterinary biotechnology"

Veterynarna biotehnologija – Veterinary biotechnology, 2018, 32(1), 313-318 [in Ukrainian]. https://doi.org/10.31073/vet_biotech32(1)-41

CHORNY M.V., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.SILINSKA O.I.e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.SHCHEPETILNIKOV Yu.O., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.MACHULA О.S.e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Kharkiv State Zooveterinary Academy


Introduction. The data of the investigations on the effect of biological microelement complexes on the resistance, immune status, productive qualities and durability of swine have been presented in the article.

Objective. The objective of the work was to study the possibility of the use of biological microelement complexes, their influence on the clinical and physiological state, natural resistance and productive qualities of the young of swine, on the production of the pork that is safe in sanitary terms.

Materials and methods. The research and production experiments have been carried out on the crossbred Large White x Landras pigs. Three groups of the animals have been formed by the analogy principle, there were 10 pigs, mean live weight 2,8±0,2 kg, in each group. The complexes that were synthesized at high temperature on the basis of microelements: iron with methionine and copper and cobalt with tryptophan produced in PE “BTU Center” have been used as biological products. The animals of the control group were injected by ferroglukin at the dose of 2 ml (200 mg F³) intramuscularly on the 3rd and 7th days in the behind-the-ear area, the animals of the experimental group 1 were administered helate complex of iron with methionine, the pigs of the experimental group 2 were injected with the complex of copper and cobalt with tryptophan in the above doses. The changes of humoral and cellular factors, natural resistance, protein composition and morphological indices of blood, biochemical parameters (catalase, total and restored glutathione, productive indices (live weight, daily live weight gain) have been studied during the experiments; the morbidity and durability of the pigs as well as microclimate parameters have been taken into consideration.

Results and discussion. The level of bactericidal and lysozymic activity of blood serum is the most important index of animal health. It has been found that the animals of the experimental group 1 had lower BASK as compared to the animals of the control group by 1,73%, the experimental group 2 – by 4,1%, LASK – by 10,5% and 18,4%, respectively. Lower number of leucocytes has been revealed in the pigs of the experimental groups by 8–22% and, on the contrary, the increase in the number of erythrocytes has been revealed as evidenced by the increase in the concentration of hemoglobin by 4–17 % as compared to the control group. The pigs of the experimental groups surpassed the animals of the control group in the protein composition of blood. The decrease in the content of the total protein in the blood serum was due to the globulin fraction and the increase – due to albumins. As a result A/G coefficient did not exceed 42, 1–43,4 that demonstrated higher resistance of the animals in the experimental groups as compared to the animals of the control group. Catalase as a test shows the provision of the animals with iron and it was higher in the pigs of the experimental groups 1 and 2 by 10,6±0,2 – 18,2±0,09 % (p < 0,05). Glutathione enhances and activates immune and antioxidant possibilities of the body, the level of glutathione in the animals of the experimental groups was 51,4 mg% on the 10th day, 60,7mg% – on the 25th day that was higher as compared to the control group. As for immunoglobulin of class A the differences were: at the age of 5 days – 11,3% and at the age of 45 days – 9,4 % (p ≤ 0,05).

Conclusions and prospects for further research. The given temperature and humidity regime and the two-phase method of pig rearing with the use of complexes of biological microelements provide the stimulation of growth, the decrease in the number of gastro-intestinal disturbances and the increase in non-specific resistance of pigs. The main task can be solved– healthy, strong and resistant pigs that are well-adapted to the environmental conditions can be grown without any drugs.

Keywords: pigs, health, biological microelements, productivity.


  1. Popkov, N.A., Fisinin, V.I., Egorov, I.A. et al. (2005). Korma i biologicheski aktivnye veshhestva [Feed and biologically active substances]. Minsk: Belaruskaja navuka [in Russian].
  2. Tsykunova, O.H. & Seryakov, I.S. (2009). Udoskonalennya mineralnoho kharchuvannya svyney za rakhunok zbahachennya ratsyona litiyem [Perfection of the mineral nutrition of pigs by enriching the diet with lithium]. Sb.nauch.tr. XVII intern.nauchno-praktychnoyi konferentsiyi (26–27 serpnya 2009) − Proceedings of the 16th International Scientific-Practical Conference. (pp. 192–194). Hrodno [in Russian].
  3. Normatyvni parametry prymishchen ta vymohy do system zabezpechennya mikroklimatu: Svynarski prymishchennya ta vymohy do system zabezpechennya mikroklimatu: Svynarski pidpryyemstva (kompleksy, fermy, mali fermy) [Normative parameters of air space and requirements for microclimate systems: Pig farms and requirements for microclimate security systems: Pig farms (complexes, farms, small farms)]. (2005). VNTP-APK-02.05.K. Kyiv: Minagropolituka [in Ukrainian].
  4. Bushоv, A.V. (2010). Rozrobka retseptur ta syntez khelatokompleksnykh soyedineniy mikroelementiv, ustranyayushchikh anemiyu porosyat u Serednevolozkomu rehioni. Sovremennye problemy intensifikatsii proizvodstva svininy v krayinakh SND [Development of the formulation and synthesis of chelate-complex compounds of microelements that eliminate the anemia of pigs in the Middle Vologda region. Modern problems of intensification of pork production in the CIS countries]. Sb. nauch. tr. XVII mizhn.nauchno-praktychnoyi konferentsiyi po svynarstvu.− Collection of scientific. works. XVII ap. Scientific and Practical Conference on Pig Production. (pp. 322–326). Ulyanovsk [in Russian].
  5. Senechyn, V.V., Belenchuk, R.V. & Oseredhchuk, R.S. (2002). Metabolizm midi v zhyvomu orhanizmi [Metabolism of copper in a living organism]. Nauk. Visnyk LDAVM im .S.Z. Hzhytskoho – S.Z. Gzhytsky Science Herald LADAVM., 4, 2, 98–106 [in Ukrainian].
  6. Stetsenko, I.I. & Kozlova, E.V. (2010). Posylennya imuno-fiziolohichnoho statusu orhanizmu porosyat pid vplyvom preparatu «YA-rost z lypydom». [Increase of the immune-physiological status of the piglets organism under the influence of the preparation "ß-growth with a lipid"] Suchasni problemy intensyfikatsiyi vyrobnytstva svynyny v krayinakh SND: Sb.nauch.tr. XVII mizhn.nauchno-praktychnoyi konferentsiyi po svynovodstva − Modern problems of intensification of pork production in the CIS countries: Sat. XVII International Scientific Conference on pig breeding. (pp. 62–266). [in Russian].
  7. Kostoglou, P. (2000). Effect of β-carotene on health status and performance of sows and their litters. Animal Nutr., 83, 3, 150–157.
  8. Shakhov, A.H. (2004). Sokhranenye porosyat pry yikh dorashchyvanni [Preservation of piglets during their growth]. Svynovodstvo − Pig breeding, 2, 15–18 [in Russian].
  9. Kokorev, V.A. (2003). Myneralnoe pytanye zhyvotnykh: mezhvuz [Mineral nutrition of animals]. Sb. nauch. trudov Mordovia State University − Collection of scientific papers of Mordovia State University, 56–57 [in Russian].
  10. Boryaev, H.I., Fedorov, Yu.N. & Nevytov, M.N. (2005). O vliyanii soedineniy selena na immunnu sistemu molodnyaku svyney [On the influence of selenium compounds on the immune system of young pigs]. Selskokhozyaystvennaya biologiya − Agricultural Biology, 4, 64–68 [in Russian].
  11. Royt, A. Blastoff, Dzh. & Myel A. (2000). Immunolohyya [Immunology]. Moscow: Mir [in Russian].

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