Bulletin "Veterinary biotechnology"

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Veterynarna biotehnologija – Veterinary biotechnology, 2018, 32(1), 394-399 [in Ukrainian]. https://doi.org/10.31073/vet_biotech32(1)-53

MІAGKA K.S., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

State Scientific and Research Institute of Laboratory Diagnostics and Veterinary and Sanitary Expertise

TKACHUK S.A., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

National University of Life and Environmental Sciences of Ukraine

ANALYSIS OF THE IMPLEMENTATION OF THE PLAN OF ANNUAL STATE MONITORING OF BALANCES OF VETERINARY PREPARATIONS AND POLLUTANTS IN HONEY

Introduction. The problem of food safety is one of the components of the national security of the state.

The goal of the work. To analyze the implementation of the plan of the annual state monitoring of residues of veterinary medicines and honey contaminants for the period from 2012 to 2017 with the submission of proposals to amend existing DSTU 4497: 2005 "Honey is natural. Technical specifications" regarding the acceptable levels of antibiotics.

Materials and methods. Accredited screening methods were used to assess the content of antibiotic residues: ELISA and HPLC and confirmatory LC-MS / MS.

Results of research and discussion. Positive (level of detection limits) in 2012 was 1 sample of honey content nitrofuran AOZ, which is 5% of all samples studied. From the group of substances B6, 7 samples of honey were found to be positive for the content of sulfamethasine, which was 4.7%. In 2013, a positive result was found in 2 samples of honey for the chloramphenicol content, which was 5% of all studied samples. Chloramphenicol is one of the most toxic antibiotics for a living organism, causing aplastic anemia and banned in Europe, the USA and Japan. Also, a positive result was 1 sample of honey for the content of nitrofurase-metabolites – SEM, which was 5%. In 2016, a positive result was found in 1 sample of honey for nitrofuran AMOZ. In 2017, a positive result was found in 1 samples of honey for the chloramphenicol content, which was 5% of all studied samples.

Conclusions and prospekts for further research. According to the analysis of the Annual State Monitoring Plan for Veterinary Medicines and Pollutants for the period from 2012 to 2017, honey samples showed a positive result for chloramphenicol, nitrofuran (AOZ, AMOZ, SEM) and sulfametazine. Looking forward to research, we are conducting studies on obtaining validation data for the quantitative determination of antibiotics in honey samples in accordance with the National Monitoring Plan for Residues of Veterinary Medicines and Honey Contaminants in 2018.

Keywords: honey, monitoring, antibiotics, regulations, directives of the European Union.

REFERENCES

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