Veterynarna biotehnologija – Veterinary biotechnology, 2019, 35, 15-21 [in Ukrainian]. https://doi.org/10.31073/vet_biotech35-02
Odessa Scientific Research Station NSC “IECVM”
THE EFFECT OF ACUTE AND CHRONIC COURSE OF DAVENIOSIS ON BIOCHEMICAL INDICATORS OF HENS’ BLOOD SERUM
Introduction. Daveniosis is a focal helminthiasis of hens. Acute disease is recorded mainly in young poultry of 2‒4 months of age, and with the older one – the chronic course of a disease. The causative agent is the Davainea proglottina cestode, which parasites in the duodenum of hens.
The goal of the work. To find out the effect of acute and chronic course of daveniosis on the biochemical parameters of blood serum of hens.
Materials and methods. Study objects: 90 days old hens, spontaneously infested with daveniosis with acute course of a disease and 130 days old hens with chronic course of a daveniosis.
Results of research and discussion. In the acute course of daveniosis, the total protein content decreased by 16.8%, albumin by 40.3%, and on the contrary globulin content increased by 8.9%. The content of α-globulins increased the most - by 15.1%, which indicates the intensity of the organismis reaction to the inflammatory process, particularly in its acute stages. A significant increase of β-globulins by 7.5% occurred, but γ-globulins by only 3.4%. The albumin-globulin ratio in the studied group was 0.6, and in the control one – 1.0. The circulating immune complex (CIC) concentration was 52.4% higher than in the control group, which indicates the development of immunosuppression in hens after being infested. In the chronic course of daveniosis, a slight decrease in total protein by 5.5%, albumin by 16.6%, and an increase in total globulin by 5.3% was recorded. Only α-globulins increased by 13.4%, β‑globulins by 0.6%, and γ-globulins by 1.2%. The CIC and seromucoids concentration increased by only 28.6% and 33.3% respectively, while in the acute course indicators increased by 52.4% and 55.6%, respectively.
Conclusions and prospects for further research. In the acute course of daveniosis, the content of total protein, albumin and the content of globulins are likely to decrease in the serum of hens due to the significant increase in α-globulins and β-globulins, which forms an A/G ratio of 0.6 versus 1.0, whereas in the chronic course of infestation the A/G ratio was 0.8. An increase in the CIC and seromucoids concentration in the acute course of invasion is two times higher than in the chronic one and indicates a greater immunosuppressive effect of helminths on the poultry’s body.
Keywords: chickens, daveniosis, blood, biochemistry.