Bulletin "Veterinary biotechnology"

Veterynarna biotehnologija – Veterinary biotechnology, 2019, 35, 135-144 [in Ukrainian]. https://doi.org/10.31073/vet_biotech35-16

SACHUK R.M., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Research Station of Epizootology IVM NAAS

STRAVSKY Y.S., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

I. Horbachevsky Ternopil National Medical University

GORYUK Yu.V., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

State Agrarian and Engineering University in Podilya

ZHIGALYUK S.V., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Research Station of Epizootology IVM NAAS

EFFICIENCY OF THE POSTPARTUM COW PATHOLOGY COMPLEX PREVENTION SCHEMES

Introduction. In the nosology of obstetric pathology of cows a special place is occupied by postpartum lesions of genitals by pathogenic microflora. The infection, which begins as a local inflammatory process, can subsequently spread through the birth canal, blood and lymphatic systems, causing not only diseases of the organs of the reproductive system, but of the whole organism.

The goal of the work was to study the effectiveness of obstetric pathology prevention schemes in cows after calving, which included use of intrauterine, hormonal and vitamin-mineral preparations.

Materials and methods. In our study we used the classical biochemical methods of blood tests and carried out identification, classification of the isolated microflora, determined the sensitivity of isolated microorganisms to antibiotics.

Results of research and discussion. E. coli, S. aureus were isolated from the lochia of pregnant cows, rarely S. saprophyticus and S. faecalis. "Ceftiozol" and "Yodozol" were the only effective preparations against all tested strains, including polyresistant S. saprohyticus and St. faecalis. After complex measures were applied to the animals of the experimental groups, the recovery of blood biochemical parameters to the limits of the reference values occurred faster than in animals of the control group. Studies showed that in cows of the 1st and 2nd experimental groups, the termination of lochia discharge observed by 9 days earlier, uterine involution – by 13 days earlier than in the cows of the control group, which led to shortening the length of the service period, which turned out to be by 8 and 10 days shorter than in animals of the control group. These animals had significantly higher fertility rates, and the insemination index was 1.2 and 1.1, which was significantly lower than in the control group – 1.5.

Conclusion and prospects for further research. The complex application of aerosols for intrauterine use “Ceftiozol”, “Iodozol” and preparations “Phytospray”, “Brorostrofan”,, “Uterodev”, “Energolit”, “Kalfomin” and “Devivit complex” showed high therapeutic efficacy. The study of procalcitonin makes it possible to evaluate efficiently and predict the course of the disease and prescribe the most appropriate treatment. In the future, it is planned to study the activity of hepatospecific enzymes of blood sera during application of these preparations for the prevention of postpartum pathology of cows.

Keywords: microflora, postpartum pathology, efficacy, Ceftiozol, Iodosol.

REFERENCES

  1. Stravsky, Y.S. (2017). Diahnostyka, likuvannia ta profilaktyka akusherskoi patolohii u koriv (metodychni rekomendatsii) [Diagnosis, treatment and prevention of obstetric pathology in cows (guidelines)]. Lviv [in Ukrainian].
  2. Sachuk, R.M., Kulinich, O.V. & Katsaraba, O.A. (2017). Efektyvnist aerozolnoho vnutrishnomatkovoho preparatu «Metrazol-bio» pry endometryti u koriv [Efficacy of Metrazol-bio aerosol intrauterine drug on cows with endometritis]. Naukovyi visnyk Lvivskoho natsionalnoho universytetu veterynarnoi medytsyny ta biotekhnolohii imeni S.Z. Gzhytskoho – Scientific Bulletin of the S.Z. Gzhytskiy Lviv National University of Veterinary Medicine and Biotechnology, 19, 82, 110-113 [in Ukrainian].
  3. Sachuk, R.M., Zhigaliuk, S.V., Tverdiy, V.M., Stravsky, Ya.S., Katyukha, S.M., Katsaraba, O.A. et al. (2018). Aerozolnyi preparat tsefalosporynovoho riadu dlia profilaktyky ta likuvannia pisliarodovykh vnutrishnomatkovykh infektsii u tvaryn [Aerosol preparation of cephalosporin series for the prevention and treatment of postpartum intrauterine infections in animals]. Ukraine Utility model patent No. 127501 [in Ukrainian].
  4. Katsaraba, O.A., Stefanik, V.Yu., Kostyshyn, E.E., Sachuk, R.M. & Kulinich, O.V. (2018). Zastosuvannia vnutrishnomatkovoho aerozolnoho preparatu dlia terapii koriv pry pisliarodovykh uskladnenniakh [The use of intrauterine aerosol preparation for the treatment of cows in postpartum complications]. Naukovyi visnyk Lvivskoho natsionalnoho universytetu veterynarnoi medytsyny ta biotekhnolohii imeni S.Z. Gzhytskoho – Scientific Bulletin of the S.Z. Gzhytskiy Lviv National University of Veterinary Medicine and Biotechnology, 20, 87, 55-59 [in Ukrainian].
  5. Nedzhanov, A.G. (1999). Fiziologiya i patologiya rodov i poslerodovogo perioda u s.-kh. Zhivotnykh [Physiology and pathology of childbirth and the postpartum period in agricultural animals]. Voronezh: VGAU [in Russian].
  6. Vos, P., Garrity, G., Jones, D., Krieg, N.R., Ludwig, W., Rainey, F.A. & Whitman, W. (Eds.). (2011). Bergey's Manual of Systematic Bacteriology: Volume 3: The Firmicutes. Springer Science & Business Media.
  7. Rokitsky, P.F. (1973). Biologicheskaya statistika [Biological statistics]. Minsk: Higher School [in Russian].

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