Bulletin "Veterinary biotechnology"

Veterynarna biotehnologija – Veterinary biotechnology, 2021, 39, 18-28 [in Ukrainian]. https://doi.org/10.31073/vet_biotech39-02

BOIKO P.K.1, е-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., NYCHYK S.A.1, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., BOIKO O.P.2, е-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., TYTIUK O.V.2, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., SHEVCHUK V.M., е-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

1Інститут ветеринарної медицини НААН
2Волинський національний університет імені Лесі Українки

IS CATTLE MYCOBACTERIOSIS AN ACCIDENTAL INFECTION OF AN INDIVIDUAL HERD OR A COMPLEX EPIDEMIOLOGICAL PROBLEM?

Introduction. Ukrainian livestock (cattle) possesses tuberculosis free status currently. However, allergically positive animals are still detected in around 180-250 tuberculosis-free farms each year. In our former study it was indicated the fact of infection with the atypical acid-resistant mycobacteria of cattle herd in a certain farm with tuberculosis-free status in Volyn oblast.

The goal of the work. Our purpose was to study peculiarities of the infectious and epizootic process caused by atypical acid resistant mycobacteria in a certain farm with tuberculosis-free status and to use some tools of epidemic and epizootic prognosis.

Materials and methods. The epizootological, allergic, clinical, pathological, histological, bacteriological and biological research methods were used.

Results of research and discussion. The results of the study showed that the false-positive tuberculin skin tests or pseudo-allergic reactions on PPD in cows was the extended asymptomatic infectious process, caused by atypical mycobacteria. This thesis was confirmed bacteriologically. M. fortuitum and M. scrofulaceum were identified from the lymph nodes of animals with of positive tuberculin skin test.

Based on the results of the study, a comprehensive approach system of measures was developed to prevent slaughtering of cows and the economic losses.

Conclusions and prospects for further research: The fact of active mycobacteriosis epizootic process in a cattle farm has been detected and confirmed.

Keywords: mycobacteriosis, cattle, tuberculin, allergic reactions, atypical acid-resistant mycobacteria, epidemic and epizootic process.

REFERENCES

  1. Busol, V.O., Blazhko, A.P., & Shevchuk, V.M. (2010). Tuberkuloz tvaryn: bibliohrafichno-referatyvnyy dovidnyk [Animal tuberculosis: bibliographic-abstract reference book]. Kyiv: Fitosotsiotsentr [in Ukrainian].
  2. Busol, V.O., Postoy, V.P., & Sitnik, V.A. (2001). Monitorynh epizootychnoyi sytuatsiyi z tuberkulʹozu velykoyi rohatoyi khudoby v krayinakh svitu [Monitoring of the epizootic situation of bovine tuberculosis in the world].  Nauk. visnyk Nats. ahrar in-tu. – Science Bulletin of the National Agricultural Institute, 42, 146-152 [in Ukrainian].
  3. Zavgorodniy, A.I., Bilushkov, V.V., & Kalashnik, M.V. (2018). Psevdoalerhichni reaktsiyi na tuberkulin u velykoyi rohatoyi khudoby [Pseudoallergic reactions to tuberculin in cattle]. Veterynarna biotekhnolohiya Veterinary biotechnology, 32(2), 176-184. [in Ukrainian].
  4. Kalashnik, M.V. (2016). Doslidzhennya biolohichnoho materialu vid velykoyi rohatoyi khudoby kulʹturalʹnym metodom na tuberkuloz [Research of biological material from cattle by a cultural method on tuberculosis]. Vet. medytsyna Vet. medicine, 102, 91-94 [in Ukrainian].
  5. Kassich, Y.Ya., & Borzyak, A.T. (1990). Tuberkulez zhivotnykh i mery borby s nim [Animal tuberculosis and control measures]. Kyiv: Urozhay [in Russian].
  6. Dyachenko, G.M., Kravchenko, N.O., & Romanenko, V.P. (2005). Problema diahnostyky tuberkulozu silskohospodarskykh tvaryn u suchasnykh umovakh. [The problem of diagnostics of tuberculosis of silskogospodarnykh tvarin in the lucky minds]. Veterynarna medytsyna Vet. medicine, 85, 1236-1240 [in Ukrainian].
  7. Boyko, P.K., Nichik, S.A., Boyko, O.P., Sitnik, V.A., & Mazur, V.M. (2020). Formuvannya infikovanosti velykoyi rohatoyi khudoby atypovymy mikobakteriyamy v okremo vzyatomu stadi [Formation of infection of cattle with atypical mycobacteria in a single herd]. Veterynarna biotekhnolohiya Veterinary biotechnology, 36, 9-21 [in Ukrainian].
  8. Boyko, P.K., Nichik, S.A., Boyko, O.P., Mandigra, Yu.M., & Shevchuk, V.M. (2020). Osoblyvosti infektsiynoho ta epizootychnoho protsesu za mikobakteriozu velykoyi rohatoyi khudoby, sprychynenoho atypovymy kyslotostiykymy mikobakteriyamy [Features of infectious and epizootic process in bovine mycobacteriosis caused by atypical acid-resistant mycobacteria]. Veterynarna biotekhnolohiya Veterinary biotechnology, 37, 7-19 [in Ukrainian].
  9. Kassich, Yu.Ya., Zavgorodny, A.I., & Kassich, V.Yu. (2004). Simultannaya allergicheskaya proba pri diagnostike tuberkuloza (Korovy, soderzhashchiyesya v krestyanskikh khozyaystvakh razlichnykh oblastey Ukrainy). [Simultaneous allergic test for the diagnosis of tuberculosis (Cows kept on farms in different regions of Ukraine)]. Veterinariya Vet. medicine, 8, 16-18 [in Russian].
  10. Pichugin, L.M., & Akulov, A.V. (1980). Praktikum po patologicheskoy anatomii selskokhozyaystvennykh zhivotnykh [Workshop on the pathological anatomy of farm animals]. Moscow: Kolos [in Russian].
  11. Skorodumov, D.I., Subbotin, V.V., Sidorov, M.A., & Kostenko, T.S. (2005). Mikrobiologicheskaya diagnostika bakterialnykh infektsiy zhivotnykh [Microbiological diagnosis of bacterial infections in animals]. Moscow: Izograph [in Russian].
  12. Yavorska, G.V., & Sibirna, R.I. (2009). Morfoloho-kulturalni i fizioloho-biokhimichni vlastyvosti atypovykh mikobakteriy [Morphological-cultural and physiological-biochemical properties of atypical mycobacteria]. Mikrobiol. zh. Microbiol. J., 71, 4, 2734 [in Russian].
  13. Starkova, D.A.  (2013). Aktualnyy vozbuditel mikobakterioza cheloveka. [The current causative agent of human mycobacteriosis]. Infek. i immunitet ‒ Inf. & Imm, 3, 7-14 [in Russian].
  14. Shevchenko, O.S., Todoriko, L.D., Poteyko, P.I., & Pogorelova, O.A. (2019). Voprosy dyahnostyky y lechenyya netuberkuleznykh mykobakteryozov [Issues of diagnosis and treatment of non-tuberculous mycobacteriosis]. Skhidno-yevropeyskyy zhurnal vnutrishnoyi ta simyeynoyi medytsyny ‒ Eastern European Journal of Internal and Family Medicine, 1, 36-53 [in Russian].
  15. Bodle, E.E., Cunningham, J.A., Della-Latta P., et al. (2008). Epidemiology of Nontuberculous Mycobacteria in Patients without HIV Infection. New York City. Emerging Infectious Diseases, 14, 3, 390-396.
  16. Cayrou, C., Turenne, C., & Behr, M.A. (2010). Genotyping of Myco­bacterium avium complex organisms using multispacer sequence typing. Microbiology, 156, 687-694.
  17. Tran, Q.T., & Han, X.Y. (2014). Subspecies Identification and Significance of 257 Clinical Strains of Mycobacterium avium. Journal of Clinical Microbiology, 52, 4, 1201-1206.
  18. Ryu, Y.J., Koh, W.-J., & Daley, C.L. (2016). Nontuberculous Mycobacterial Lung Disease: Clinicians’ Perspectives. Tuberc Respir Dis (Seoul), 79 (2), 74-84.

Download full text in PDF