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Veterynarna biotekhnolohiia– Veterinary biotechnology, 2023, 42, 33-42 [in Ukrainian]. https://doi.org/10.31073/vet_biotech42-04

ZHOVNIR A. M., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it., MYNTSIUK E. P., e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Institute of Veterinary Medicine of the NAAS

 

MANNHEIMIA HAEMOLYTICA AS A CAUSE OF RESPIRATORY DISEASES IN SHEEP (REVIEW)

Introduction. Respiratory diseases cause significant economic losses to the livestock and goat industries worldwide. In the United States alone, this amount ranges from 1-3 billion USD annually. These diseases can occur as enzootic or sometimes as epizootic, making them a problem for agricultural enterprises. Until recently, the microorganism known as Pasteurella haemolytica, which was associated with respiratory disease in cattle, as well as respiratory disease and septicemia in sheep, has been reclassified as a separate genus Mannheimia.

The goal of the work is analysis the literature regarding the prevalence, etiological factors, and pathogenesis of sheep respiratory diseases caused by Mannheimia haemolytica.

Materials and methods. The study was conducted by analyzing foreign sources devoted to this problem.

Results of research and discussion. Mannheimiosis is a factor-infectious disease caused by the microorganism Mannheimia haemolytica, primarily affecting ruminants and accompanied by respiratory system damage. Certain predisposing stress factors causing its emergence. The most susceptible animals are primarily ruminants, including cattle, sheep, goats, yaks, buffalo, bison, mules, camels, donkeys, llamas, alpacas, and zebus.

Currently, M. haemolytica biotype A includes 12 serotypes A (A1, A2, A5, A6, A7, A8, A9, A12, A13, A14, A16, and A17) of which serotypes A1 and A2 have the most widespread and epidemiological significance, and 4 serotypes T.

Isolates of biotype A haemolytica are capable of causing respiratory disease and mastitis in cattle and sheep and septicemia in lambs, isolates of biotype T cause septicemia in young sheep, although it was classified as M. trehalosi.

The main symptoms of the disease associated with the development of respiratory syndrome occur in three phases: fever, respiratory system damage and septicemia. In sheep and goats a mastitic form of infection is also encountered.

Therapy for the disease involves usage of antimicrobial and anti-inflammatory agents.

Active prevention involves the usage of vaccines that protectanimals, and more importantly, reduces the circulation of the pathogen and reduces stress and eliminatesfactors that contribute to the disease.

Conclusions and prospects for further research. Mangeimiosis is a commondisease in sheep farms both in the world and in Ukraine. The difficulty indiagnosis and lack of information about this disease leads to the fact that veterinarians often make false diagnoses on the basis of which they develop measures toeliminate and prevent the disease. Prospects for further research – creation and testing of a polyvalent prophylactic agent against respiratory andclostridial diseases of sheep.

Keywords: Mannheimia haemolytica, Pasteurella multocida, bacterial pathogenesis, respiratory diseases.

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